Genetically Guided Prescribing: Genetically Based Adverse Medication Reactions by Dr Ajeet Singh

Prof Ajeet Singh is an academic private psychiatrist whose research has focused on genetically guided prescribing (pharmacogenetics) of antidepressants, particularly the role of the blood-brain-barrier. Dr Singh is the Founder of CNSDose, an academic member of the Clinical Pharmacogenetics Implementation Consortium (CPIC), and member of the Genetic Tests in Psychiatry Taskforce, International Society of Psychiatric Genetics (ISPG).

Take-Home Points

• Affordable, genetic testing is available for HLA-genotyping for carbamazepine.

• Methylation studies are important in determining impaired antidepressant treatment response.

• The relationship between methylation and psychotropic use is unknown.

Ajeet Singh,Adverse Reactions,anticonvulsants,psychotropic pharmacogenetics,carbamazepine,